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Trials in children
1Hopital Saint Vincent de Paul, 74-82 Avenue Denfert-Rochereau, 75674, Cedex 14, Paris, France. o.dulac@spv.ap-hop-paris.fr
Epilepsy Research
|July 20, 2001
Abstract:
Over 20% of epilepsies in children are intractable, and are frequently associated with deterioration of motor and cognitive functions. Some are similar to those seen in adults, but many age-related epilepsies occur only in children. Therefore, a sizeable proportion of intractable epilepsies of childhood are different from those encountered in adults, and there is an urgent need for antiepileptic drug trials to be undertaken in children at an early stage of development. An ethical framework within which these trials can be conducted has been defined.