Hematogenous pyogenic facet joint infection

A J Muffoletto1, L M Ketonen, J T Mader

  • 1Department of Orthopaedics and Rehabilitation, University of Texas Medical Branch, Galveston, Texas 77555-0792, USA.

Spine
|July 20, 2001
PubMed
Abstract

Insights

Hematogenous pyogenic facet joint infections are rare but often underdiagnosed. Early diagnosis and treatment, including percutaneous drainage and antibiotics, improve outcomes, while severe cases require surgical intervention.

Area of Science:

  • Spine surgery
  • Infectious diseases
  • Radiology

Background:

  • Hematogenous pyogenic facet joint infections are rare, with limited data on incidence, presentation, and treatment.
  • Only 27 cases were previously documented, highlighting the need for further research.

Purpose of the Study:

  • To determine the incidence, clinical presentation, diagnostic values, imaging characteristics, and optimal treatment for these infections.
  • To combine institutional data with published cases for a comprehensive analysis.

Main Methods:

  • Retrospective review of cases treated at a single institution.
  • Inclusion of previously published cases to augment the dataset.
  • Analysis of clinical characteristics, laboratory values, imaging findings, and treatment responses.

Main Results:

  • Six cases (4%) identified out of 140 spinal infections. Average age 55, 97% lumbar spine involvement.
  • 25% developed epidural abscesses, 38% severe neurologic deficits. Staphylococcus aureus was common.
  • MRI accurately identified infections. Percutaneous drainage (85% success) showed higher, though not statistically significant, success than antibiotics alone (71%).

Conclusions:

  • Hematogenous pyogenic facet joint infection is rare, underdiagnosed, and can lead to epidural abscesses and neurologic deficits.
  • Percutaneous drainage with antibiotics may offer better outcomes than antibiotics alone for uncomplicated cases.
  • Immediate decompressive laminectomy is crucial for cases with epidural abscess and severe neurologic compromise.

Related Concept Videos

Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Streptococcal Pharyngitis01:27

Streptococcal Pharyngitis

Streptococcal pharyngitis, commonly known as “strep throat,” is an acute infection of the oropharyngeal tissues caused by the Gram‑positive Group A Streptococcus (Streptococcus pyogenes). Transmission occurs primarily through respiratory droplets expelled during coughing, sneezing, or talking.Mechanisms of Host Entry and Immune EvasionUpon entering the host, S. pyogenes adheres to the mucosal epithelial cells of the pharynx via surface proteins, notably lipoteichoic acid and the antiphagocytic...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Bacterial Meningitis II: Pathophysiology01:26

Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...