Cancer and children: where are we coming from? Where are we going?

The past four decades have seen remarkable progress in the treatment of childhood cancer and changes in the social environment in which cancer in the family is experienced. Current research in pediatric psycho-oncology focuses on psychosocial consequences of the disease and on differentiating which factors predict problematic versus positive outcomes in adjustment of the child and the family. The papers in this Special Issue reflect much of the recent developments in childhood psycho-oncology as well as the challenges to come.