Related Experiment Video

Updated: Jul 16, 2026

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
10:29

Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons

Published on: October 8, 2014

[3H]N-2-(4-(N-benzamido)phenyl)propyl-2-propanesulfonamide: a novel AMPA receptor potentiator and radioligand

H Zarrinmayeh, D Bleakman, M R Gates

    Journal of Medicinal Chemistry
    |July 21, 2001
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
    11:01

    Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase

    Published on: November 23, 2016

    Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
    07:16

    Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

    Published on: August 16, 2018

    Related Experiment Videos

    Last Updated: Jul 16, 2026

    Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons
    10:29

    Multi-photon Intracellular Sodium Imaging Combined with UV-mediated Focal Uncaging of Glutamate in CA1 Pyramidal Neurons

    Published on: October 8, 2014

    Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
    11:01

    Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase

    Published on: November 23, 2016

    Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
    07:16

    Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

    Published on: August 16, 2018

    Related Concept Videos

    Adrenergic Agonists: Chemistry and Structure-Activity Relationship01:16

    Adrenergic Agonists: Chemistry and Structure-Activity Relationship

    Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine moiety with an aromatic ring and an ethylamine side chain.
    Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
    Separation of the aromatic...

    Articles linked to this work by shared authors, journal, and citation graph.

    AMPA receptors in the therapeutic management of depression.

    CNS & neurological disorders drug targets·2007

    AMPA receptor potentiators as novel antidepressants.

    Current pharmaceutical design·2005

    LY293558, a novel AMPA/GluR5 antagonist, is efficacious and well-tolerated in acute migraine.

    Cephalalgia : an international journal of headache·2004

    Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro.

    Neuropharmacology·2004

    Kainate receptor agonists, antagonists and allosteric modulators.

    Current pharmaceutical design·2002

    A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP.

    Neuron·2001

    Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

    Journal of medicinal chemistry·2026

    A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

    Journal of medicinal chemistry·2026

    From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

    Journal of medicinal chemistry·2026

    Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

    Journal of medicinal chemistry·2026

    Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

    Journal of medicinal chemistry·2026

    Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

    Journal of medicinal chemistry·2026

    Micro- and nanoscale focusing across the extreme ultraviolet range of the ASTRID2 light source with a capillary optic.

    The Review of scientific instruments·2026

    Real-space imaging of valence-electron bonding dynamics with ultrafast hard X-ray scattering.

    Faraday discussions·2026

    Blue magnetophosphene perception under subthreshold magnetic stimulation in a human retinal degeneration model.

    Frontiers in neuroscience·2026

    Observation of Antichiral Hinge States in a Three-dimensional Gyromagnetic Photonic Crystal.

    Nature communications·2026

    Photoelectron Imaging Spectroscopy of Ta4On - (n = 0-9) Clusters.

    Chemphyschem : a European journal of chemical physics and physical chemistry·2026

    Temperature and pressure sensing properties based on FIR method modified by multiphoton processes in lead-free halide double perovskites.

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us