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Characteristics and course of urinary tract dysfunction after acute transverse myelitis in

V Ganesan1, M Borzyskowski

  • 1The Wolfson Centre, London, UK. V.Ganesan@ich.ucl.ac.uk

Developmental Medicine and Child Neurology
|July 21, 2001
PubMed

Insights

Pediatric transverse myelitis often causes bladder issues, including obstructive and irritative urinary tract symptoms. Bladder dysfunction recovery in children with transverse myelitis was independent of motor recovery.

Area of Science:

  • Pediatric Neurology
  • Urology
  • Neuro-Urology

Background:

  • Bladder dysfunction is a frequent complication of transverse myelitis.
  • Limited data exists on the characteristics and natural history of bladder involvement in pediatric transverse myelitis.
  • Understanding bladder issues is crucial for managing pediatric neurological conditions.

Purpose of the Study:

  • To characterize bladder involvement in children diagnosed with acute transverse myelitis.
  • To investigate the natural history of bladder dysfunction in this pediatric cohort.
  • To explore the relationship between bladder function recovery and neurological outcome.

Main Methods:

  • Study included ten children (8 months to 16 years) with acute transverse myelitis.
  • Utilized video urodynamics to assess bladder function.
  • Followed patients in a tertiary pediatric neurourology clinic for a median of 36 months.

Main Results:

  • Nine out of ten children presented with obstructive urinary tract symptoms.
  • Most patients developed irritative urinary tract symptoms approximately one month post-presentation.
  • Video urodynamics revealed combined irritative (detrusor hyperreflexia) and obstructive (detrusor-sphincter dyssynergia) abnormalities.
  • All patients experienced residual bladder dysfunction; only four were asymptomatic with treatment.
  • Recovery of bladder function was not correlated with the degree of motor recovery.

Conclusions:

  • Pediatric transverse myelitis frequently leads to complex bladder dysfunction involving both irritative and obstructive components.
  • Video urodynamics is valuable for targeted management of bladder issues in affected children.
  • Significant residual bladder dysfunction persists despite treatment, and its recovery is independent of motor function recovery.

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