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[Oxygen consumption in infants and children with congenital heart defects]
Insights
Resting oxygen uptake in children with congenital heart disease showed a trend towards higher values but no statistically significant difference from standard metabolic rates. Factors influencing oxygen consumption in these children are discussed.
Area of Science:
- Pediatric Cardiology
- Physiology
- Metabolic Research
Context:
- Congenital heart disease (CHD) affects children's physiological functions.
- Accurate assessment of resting oxygen uptake is crucial for managing pediatric cardiac conditions.
- Understanding metabolic rates in children with CHD informs clinical practice.
Purpose:
- To determine resting oxygen uptake in children with and without congenital heart disease.
- To compare measured oxygen uptake values against established basal metabolic rate standards.
- To explore factors potentially influencing oxygen consumption in pediatric cardiac patients.
Summary:
- Resting oxygen uptake was measured using a diaferometer in 90 children with congenital heart disease (CHD) and 39 controls, aged 1 month to 15 years.
- Values were normalized to body surface area and compared to Karlberg and Fleisch standards.
- While a tendency for higher resting oxygen uptake was observed in children with CHD, no statistically significant difference from standard values was found.
Impact:
- Highlights the need for further research into specific factors affecting oxygen uptake in pediatric CHD.
- Provides baseline data for understanding metabolic status in children with cardiac defects.
- Informs potential adjustments in clinical monitoring and therapeutic strategies for children with CHD.
Abstract:
Resting oxygen uptake was determined by a diaferometer in 90 children with congenital heart disease and in 39 children without cardiac defects, both groups ranging in age from 1 month to 15 years. The children with cardiac defects were classified according to the kind of the defect. The values of all children were related to body surface area and in every case compared with standards of basal metabolic rate of Karlberg and Fleisch. Although there was a tendency to higher values of resting oxygen uptake in children with cardiac defects, a statistically definite difference to the standard values could not be established. The possibly influencing factors of oxygen uptake in children with cardiac defects, as weight reduction, sedation, heart dynamics and oxygen cost of breathing are discussed regarding the literature.