Related Experiment Video
Updated: Aug 2, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
Published on: June 26, 2020
Hepatitis B and C viruses and sexually transmitted disease patients in Jamaica
M Smikle1, G Dowe, T Hylton-Kong
1Department of Microbiology, The University of the West Indies, Kingston 7, Jamaica. msmikle@uwimona.edu.jm
Insights
This study found no evidence of sexual transmission for hepatitis C virus (HCV) or hepatitis B virus (HBV) in Jamaican STD clinics. Further multicenter research is recommended to clarify transmission routes.
Area of Science:
- Infectious Diseases
- Hepatology
- Virology
Background:
- Hepatitis C virus (HCV) and hepatitis B virus (HBV) pose significant global health challenges.
- Understanding transmission routes, including sexual transmission, is crucial for effective public health interventions.
- Sexually transmitted disease (STD) clinics are key sites for monitoring viral infections within high-risk populations.
Purpose of the Study:
- To investigate the prevalence of HCV, HBV, and HIV infections in Jamaican STD clinics.
- To identify potential risk factors associated with HCV and HBV infections in this population.
- To assess the role of sexual transmission in the epidemiology of HCV and HBV in Jamaica.
Main Methods:
- A prospective observational cohort study was conducted with 485 consecutive patients in Kingston, Jamaica.
- Blood samples were analyzed for antibodies to HCV (anti-HCV), hepatitis B core antigen (anti-HBc), hepatitis B surface antigen (HBsAg), HIV-1, and syphilis.
- Sociodemographic and sexual characteristics were collected to evaluate risk factors for HCV and HBV.
Main Results:
- No cases of anti-HCV antibodies were detected.
- Prevalence rates were: anti-HBc (21.0%), HBsAg (3.2%), HIV-1 (2.5%), and syphilis (5.2%).
- Advanced age was the sole independent risk factor for anti-HBc positivity.
Conclusions:
- The study findings do not support sexual transmission as a significant route for HCV or HBV in Jamaica.
- Further well-designed, multicenter studies are needed to provide more definitive information on the sexual transmission of these viruses.
- Current data suggest focusing on other transmission routes for HCV and HBV in the Jamaican context.
Objectives:
To determine the prevalence of hepatitis C virus (HCV), hepatitis B virus (HBV), human immunodeficiency virus (HIV) infections, and risk factors for HCV and HBV infections in sexually transmitted disease (STD) clinics in Jamaica.
Methods:
A prospective observational cohort study was carried out. Blood was collected from 485 consecutive patients attending the comprehensive health centre in Kingston, Jamaica. Serum was tested using commercially prepared reagents and standard procedures for antibodies to HCV (anti-HCV), hepatitis B core antigen (anti-HBc), hepatitis B surface antigen (HBsAg), HIV-1 infection, and syphilitic infection. Sociodemographic and sexual characteristics of the patients were recorded for assessment as risk factors for HCV and HBV infections.
Results:
None of the patients had anti-HCV, 21.0% had anti-HBc, 3.2% HBsAg, 2.5% tested positive for HIV-1, and 5.2% had reactive serological test for syphilis. Age was the only independent risk factor identified for anti-HBc positivity.
Conclusions:
The data obtained in this study were not in support of sexual transmission of HCV or HBV infections in Jamaica. Carefully designed multicentre studies could provide more consistent information on the transmission of these viruses by sexual routes.
Related Concept Videos
Sexually Transmitted Infections
Infectious Diseases and Their Occurrence
Hepatitis
Genital Herpes
Amebiasis
Viral Hepatitis I: Introduction

