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Updated: Jul 22, 2026

Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation
Published on: July 23, 2014
Emergency pulmonary autograft mitral valve replacement in a child
M B Mitchell1, G S Maharajh, M R Bielefeld
1Division of Cardiothoracic Surgery, The Children's Hospital, Denver, Colorado 80218, USA. mitchell.max@tchden.org
Abstract:
Mitral valve replacement in small children imposes significant clinical difficulties because of the relatively small mechanical prosthetic valves required and the need for lifelong anticoagulation therapy. A child weighing 10.4 kg presented with thrombosis of her 19-mm mechanical mitral prosthesis 4 weeks after implantation despite appropriate oral anticoagulation therapy. An emergency mitral valve replacement with a pulmonary autograft was successfully performed with encouraging short-term results.
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