Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Aortic root replacement versus aortic valve replacement: a case-match study.

P P Urbanski1, M Wagner, M Zacher

  • 1Herz- und Gefaess-Klinik, Bad Neustadt, Germany. urbanski@kardiochirurg.de

The Annals of Thoracic Surgery
|July 24, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hereditary multiple exostoses (EXT): mutational studies of familial EXT1 cases and EXT-associated malignancies.

American journal of human genetics·1997
Same author

Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum.

International journal of cancer·1996
Same author

Periodic limb movements as the initial manifestation of restless legs syndrome triggered by lumbosacral radiculopathy.

Sleep·1996
Same author

IVF: out-of-date evidence, or not.

Lancet (London, England)·1996
Same author

Congenital muscular dystrophy with laminin alpha 2 chain deficiency: identification of a new intermediate phenotype and correlation of clinical findings to muscle immunohistochemistry.

European journal of pediatrics·1996
Same author

[Early manifestation of polycystic kidney changes in tuberous sclerosis].

Der Pathologe·1996
Same journal

Does prior percutaneous coronary revascularization negatively affect the outcomes of subsequent coronary artery bypass grafting?

The Annals of thoracic surgery·2026
Same journal

Lymph Node Dissection and Chylothorax - Balancing Oncologic Benefit Against Morbidity.

The Annals of thoracic surgery·2026
Same journal

Preserved Antegrade Pulmonary Blood Flow in Bidirectional Glenn: Outcomes and Considerations for Staged Palliation.

The Annals of thoracic surgery·2026
Same journal

Domo Arigato, Mr. Roboto.

The Annals of thoracic surgery·2026
Same journal

Impact of High SUVmax on Recurrence by Resection Strategy in Stage IA Adenocarcinoma ≤2 cm.

The Annals of thoracic surgery·2026
Same journal

Preoperative Treatment for Stage II NSCLC Requires Multidimensional Consideration.

The Annals of thoracic surgery·2026
See all related articles

Aortic root replacement combined with aortic valve replacement has similar risks and outcomes as isolated aortic valve replacement. This complex surgery is a safe option for patients with aortic valve disease and ascending aorta dilation.

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Disease Management

Background:

  • Patients with aortic valve disease and ascending aorta dilation face risks of dissection or rupture if the aorta is not addressed during valve replacement.
  • Surgical decisions must weigh the risks of complex aortic root replacement against isolated aortic valve replacement.

Purpose of the Study:

  • To compare the early and late postoperative risks of aortic root replacement versus isolated aortic valve replacement.
  • To determine if a more complex procedure increases patient risk.

Main Methods:

  • A matched-pair study compared 100 patients undergoing aortic valve and ascending aorta replacement (CarboSeal group) with 100 patients undergoing isolated aortic valve replacement (CarboMedics group).
  • Follow-up averaged 37-38 months. Survival and morbidity were analyzed using Kaplan-Meier analysis and Cox regression.

Related Experiment Videos

Main Results:

  • Early postoperative mortality was low and not significantly different (1% vs 4%).
  • While 5-year survival was lower in the CarboSeal group (60.7% vs 86.3%), freedom from cardiac mortality and valve-related morbidity was similar between groups.

Conclusions:

  • Aortic valve and ascending aorta replacement can be performed with comparable operative risk to isolated aortic valve replacement.
  • The study supports aortic root replacement as a safe procedure regarding morbidity and late mortality.