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Related Experiment Video

Updated: Jul 18, 2026

Direct Observation of Phagocytosis and NET-formation by Neutrophils in Infected Lungs using 2-photon Microscopy

Direct Observation of Phagocytosis and NET-formation by Neutrophils in Infected Lungs using 2-photon Microscopy

Published on: June 2, 2011

Foreign body aspiration diagnosed by microscopy.

W G Kuschner¹, P S Sarinas, R Chitkara

¹Medical Service, Veterans Affairs Palo Alto Health Care System, Stanford University, School of Medicine, California 94304, USA. kuschner@stanford.edu

The American Journal of the Medical Sciences

|July 24, 2001

Summary

A rare case of adult foreign body aspiration was diagnosed through microscopic analysis of a retrieved sample. This led to the successful removal of a peanut, resolving persistent pneumonia and weight loss.

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Area of Science:

Pulmonology
Diagnostic Pathology

Background:

Adult foreign body aspiration is uncommon, often presenting with vague symptoms like persistent pneumonia.
Delayed diagnosis can lead to significant morbidity, including weight loss and misdiagnosis.

Observation:

A 50-year-old male presented with a 5-month history of weight loss and nonresolving right lower lobe pneumonia.
Initial flexible bronchoscopy with biopsy failed to diagnose the foreign body, leading to a suspected endobronchial tumor diagnosis due to bleeding complications.

Findings:

Microscopic examination of the biopsy specimen revealed vegetable matter, prompting further investigation.
Rigid bronchoscopy successfully retrieved a peanut from the bronchus intermedius.
Post-retrieval antibiotic treatment led to complete clinical and radiographic recovery.

Implications:

Microscopic analysis of retrieved samples is a crucial diagnostic tool for suspected foreign body aspiration in adults.
Early and accurate diagnosis of foreign body aspiration is essential for effective management and patient recovery.
This case highlights the importance of considering foreign body aspiration in adults with unexplained respiratory symptoms.