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Updated: Sep 21, 2026

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay
11:09

EPA Method 1615. Measurement of Enterovirus and Norovirus Occurrence in Water by Culture and RT-qPCR. II. Total Culturable Virus Assay

Published on: September 11, 2016

An outbreak of echovirus 11 in a children's home

E Somekh1, T Shohat, R Handsher

  • 1The Pediatric Infectious Diseases Unit, The Edith Wolfson Medical Center, Holon, Israel.

Epidemiology and Infection
|July 27, 2001
PubMed

Insights

Echovirus 11 efficiently spread in a children's home, causing aseptic meningitis in 30% of infected infants. Asymptomatic infections were common in infants and staff, highlighting transmission risks in communal settings.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Virology

Background:

  • Echovirus 11 outbreaks can occur in institutional settings.
  • Children's homes present unique challenges for infection control.

Purpose of the Study:

  • To investigate the transmission dynamics and clinical presentation of echovirus 11 in a children's home setting.
  • To assess the attack rate and risk factors associated with echovirus 11 infection.

Main Methods:

  • Case identification and clinical assessment of affected children and staff.
  • Laboratory analysis of cerebrospinal fluid (CSF) and stool samples for echovirus 11.
  • Serological testing to detect recent echovirus 11 infection in staff.

Main Results:

  • Echovirus 11 infection was confirmed in 9 infants younger than 1 year, with 3 developing aseptic meningitis.
  • Asymptomatic shedding of echovirus 11 occurred in 6 infants and 1 older child.
  • Seven asymptomatic staff members showed serological evidence of recent echovirus 11 infection, suggesting efficient transmission.

Conclusions:

  • Echovirus 11 spreads efficiently in children's homes, posing a significant risk to vulnerable infants.
  • Aseptic meningitis occurred in 30% of infected infants, while adult infections were largely asymptomatic.
  • Enhanced hygiene and infection control measures are crucial in institutional settings to prevent echovirus outbreaks.

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