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Hippocampal sclerosis following brief generalized seizures in adulthood
R S Briellmann1, M R Newton, R M Wellard
1Brain Research Institute, Austin and Repatriation Medical Center, and University of Melbourne, Australia.
Neurology
|July 27, 2001
Abstract:
This report describes a patient who had a first generalized tonic clonic seizure (GTCS) at the age of 18 years. The initial MRI scan was normal on visual and quantitative examination. After a further six GTCS, a second MRI scan showed reduced hippocampal volume and increased hippocampal T2 signal, which was confirmed in a third scan. Therefore, hippocampal sclerosis may be acquired in adulthood after brief GTCS.