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PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in
J W Varni1, M Seid, P S Kurtin
1Center for Child Health Outcomes, Children's Hospital and Health Center, San Diego, California, USA. jvarni@chsd.org
Insights
The Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales demonstrate reliable and valid measurement of health-related quality of life in children. These scales are suitable for diverse pediatric populations in various health settings.
Area of Science:
- Pediatric Health Outcomes Research
- Psychometrics
- Health-Related Quality of Life (HRQOL) Measurement
Background:
- The Pediatric Quality of Life Inventory (PedsQL) is a modular instrument for assessing HRQOL in children and adolescents aged 2-18.
- The PedsQL 4.0 Generic Core Scales comprise 23 items for self-report and parent proxy-report, designed for integration with disease-specific modules.
- These scales are applicable to healthy children and adolescents, as well as those with acute or chronic health conditions.
Purpose of the Study:
- To evaluate the measurement properties of the PedsQL 4.0 Generic Core Scales.
- To assess the reliability and validity of the PedsQL 4.0 Generic Core Scales in a pediatric population.
- To determine the applicability of the PedsQL 4.0 Generic Core Scales across different pediatric groups.
Main Methods:
- Administered the PedsQL 4.0 Generic Core Scales (Physical, Emotional, Social, School) to 963 children and 1,629 parents.
- Conducted item-level and scale-level measurement property analyses.
- Employed known-groups method, correlations with morbidity indicators, and factor analysis to assess validity.
Main Results:
- Achieved acceptable internal consistency reliability for Total Scale Score (child: 0.88, parent: 0.90) and summary scores.
- Demonstrated validity through known-groups comparisons, correlations with illness burden, and factor analysis.
- The PedsQL 4.0 effectively distinguished between healthy children and pediatric patients, aligning with theoretical scales.
Conclusions:
- The PedsQL 4.0 Generic Core Scales are reliable and valid instruments for measuring pediatric HRQOL.
- These scales are suitable for use in clinical trials, research, clinical practice, and school health settings.
- The PedsQL 4.0 Generic Core Scales can be applied to healthy and pediatric patient populations in community settings.
Background:
The PedsQL (Pediatric Quality of Life Inventory) (Children's Hospital and Health Center, San Diego, California) is a modular instrument for measuring health-related quality of life (HRQOL) in children and adolescents ages 2 to 18. The PedsQL 4.0 Generic Core Scales are multidimensional child self-report and parent proxy-report scales developed as the generic core measure to be integrated with the PedsQL Disease-Specific Modules. The PedsQL 4.0 Generic Core Scales consist of 23 items applicable for healthy school and community populations, as well as pediatric populations with acute and chronic health conditions.
Methods:
The 4 PedsQL 4.0 Generic Core Scales (Physical, Emotional, Social, School) were administered to 963 children and 1,629 parents (1,677 subjects accrued overall) recruited from pediatric health care settings. Item-level and scale-level measurement properties were computed.
Results:
Internal consistency reliability for the Total Scale Score (alpha = 0.88 child, 0.90 parent report), Physical Health Summary Score (alpha = 0.80 child, 0.88 parent), and Psychosocial Health Summary Score (alpha = 0.83 child, 0.86 parent) were acceptable for group comparisons. Validity was demonstrated using the known-groups method, correlations with indicators of morbidity and illness burden, and factor analysis. The PedsQL distinguished between healthy children and pediatric patients with acute or chronic health conditions, was related to indicators of morbidity and illness burden, and displayed a factor-derived solution largely consistent with the a priori conceptually-derived scales.
Conclusion:
The results demonstrate the reliability and validity of the PedsQL 4.0 Generic Core Scales. The PedsQL 4.0 Generic Core Scales may be applicable in clinical trials, research, clinical practice, school health settings, and community populations.
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