Related Experiment Video
Updated: Aug 16, 2026

Performing and Processing FNA of Anterior Fat Pad for Amyloid
Published on: October 30, 2010
Localized amyloid deposition in trigger finger
S Cordiner-Lawrie1, J Diaz, P Burge
1Nuffield Orthopaedic Centre, Oxford, UK.
Abstract:
Trigger finger is due to degeneration and thickening of the proximal portion (A1 pulley) of the flexor tendon sheath, which causes constriction of the flexor tendon. This study reports the presence of localized amyloid deposition in the tendon sheath of 11 of 47 cases (23%) of idiopathic primary trigger finger. Amyloid deposits were only found in patients aged over 46 years old and were present around cells and at sites of mucinous and fibrinoid degeneration which contained highly sulphated glycosaminoglycans. The pathogenic significance of these deposits is uncertain but their small size and presence only in middle-aged and elderly adults suggests that they represent a form of age-associated amyloid deposition.
Related Concept Videos
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Diabetic Neuropathy
Alzheimer Disease ll: Pathophysiology

