Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

RACE - Rapid Amplification of cDNA Ends02:35

RACE - Rapid Amplification of cDNA Ends

Rapid Amplification of cDNA Ends, or RACE, is one of the most effective methods to obtain a full-length cDNA from an mRNA sequence between a known internal region to the unknown sequence at the 5’ or 3’ end. The unknown region is cloned in the cDNA by a gene-specific primer that binds the known end, and a hybrid primer that attaches a predefined anchor sequence to the unknown end of the cDNA. The sequence in between is amplified by PCR with an anchor primer and a gene-specific primer.
Since the...
Stratified Sampling Method01:16

Stratified Sampling Method

Sampling is a technique to select a portion (or subset) of the larger population and study that portion (the sample) to gain information about the population. The sampling method ensures that samples are drawn without bias and accurately represent the population. Because measuring the entire population in a study is not practical, researchers use samples to represent the population of interest.
To choose a stratified sample, divide the population into groups called strata and then take a...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation01:24

One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation

This lesson introduces two critical methods in pharmacokinetics, the Wagner-Nelson and Loo-Riegelman methods, used for estimating the absorption rate constant (ka) for drugs administered via non-intravenous routes. The Wagner-Nelson method relates ka to the plasma concentration derived from the slope of a semilog percent unabsorbed time plot. However, it is limited to drugs with one-compartment kinetics and can be impacted by factors like gastrointestinal motility or enzymatic degradation.
On...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 127 ppb.

Physical review letters·2025
Same author

A compact frozen-spin trap for the search for the electric dipole moment of the muon.

The European physical journal. C, Particles and fields·2025
Same author

Molecular characterization and virulence of fungal pathogens associated with mass mortalities in hilsa Shad (Tenualosa ilisha).

Scientific reports·2025
Same author

Anomalous spin precession systematic effects in the search for a muon EDM using the frozen-spin technique.

The European physical journal. C, Particles and fields·2024
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 0.20 ppm.

Physical review letters·2023
Same author

Coronavirus peplomer interaction.

Physics of fluids (Woodbury, N.Y. : 1994)·2022

Related Experiment Video

Updated: Jun 29, 2026

Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects
08:13

Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects

Published on: May 10, 2019

Estimation of race admixture--a new method.

R Chakraborty

    American Journal of Physical Anthropology
    |May 1, 1975
    PubMed
    Summary

    This study estimates parental population contribution to hybrid gene pools using gene identity probability. It analyzes admixture dynamics, considering population size fluctuations, with an example from Cherokee Indians.

    Area of Science:

    • Population Genetics
    • Quantitative Genetics
    • Human Genetics

    Background:

    • Hybrid populations form through interbreeding between distinct parental groups.
    • Understanding the genetic contribution of parental populations is crucial for evolutionary and demographic studies.
    • Finite population size introduces stochastic fluctuations in genetic makeup.

    Purpose of the Study:

    • To estimate the contribution of parental populations to a hybrid population's gene pool.
    • To analyze the dynamics of admixture accumulation in hybrid populations.
    • To incorporate the effects of finite population size on admixture dynamics.

    Main Methods:

    • Utilizing the probability of gene identity to quantify admixture.
    • Developing a population-level model for admixture dynamics.

    More Related Videos

    Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish
    05:41

    Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish

    Published on: January 28, 2020

    A Contrast of Three Inoculation Techniques used to Determine the Race of Unknown Fusarium oxysporum f.sp. niveum Isolates
    11:48

    A Contrast of Three Inoculation Techniques used to Determine the Race of Unknown Fusarium oxysporum f.sp. niveum Isolates

    Published on: October 28, 2021

    Related Experiment Videos

    Last Updated: Jun 29, 2026

    Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects
    08:13

    Using the Race Model Inequality to Quantify Behavioral Multisensory Integration Effects

    Published on: May 10, 2019

    Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish
    05:41

    Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish

    Published on: January 28, 2020

    A Contrast of Three Inoculation Techniques used to Determine the Race of Unknown Fusarium oxysporum f.sp. niveum Isolates
    11:48

    A Contrast of Three Inoculation Techniques used to Determine the Race of Unknown Fusarium oxysporum f.sp. niveum Isolates

    Published on: October 28, 2021

  • Incorporating stochastic fluctuations due to finite population size.
  • Main Results:

    • A method is presented to estimate parental gene pool contribution at the population level.
    • The study models the dynamics of admixture accumulation, accounting for random genetic drift.
    • The methodology is demonstrated using admixture data from the Cherokee Indian population.

    Conclusions:

    • The developed method provides a robust framework for quantifying admixture in hybrid populations.
    • Finite population size significantly influences admixture dynamics and requires specific modeling approaches.
    • The study offers insights into the genetic history and admixture patterns of the Cherokee Indians.