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Calcium signalling: store-operated channel found at last
1MRC Secretory Control Research Group, The Physiological Laboratory, University of Liverpool, Crown Street, L69 3BX, Liverpool, UK. o.h.petersen@liv.ac.uk
Current Biology : CB
|July 27, 2001
Abstract:
The intestinal Ca(2+) transport protein CaT1 has recently been shown to have the biophysical characteristics of the Ca(2+)-release activated Ca(2+) channel that refills internal Ca(2+) stores following agonist-elicited release. This finding highlights a hitherto unrecognized link between epithelial Ca(2+) transport and Ca(2+) signalling.