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Posterior corneal surface changes after refractive surgery.

E Hernández-Quintela1, S Samapunphong, B F Khan

  • 1Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

Ophthalmology
|July 27, 2001
PubMed
Summary
This summary is machine-generated.

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Changes in the posterior cornea after laser vision correction (LASIK and PRK) were similar to natural variations observed in non-surgery eyes. This suggests refractive surgery does not significantly alter posterior corneal curvature beyond expected changes.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Refractive Surgery

Background:

  • Laser vision correction procedures like LASIK and PRK aim to reshape the cornea for improved vision.
  • Understanding changes to the posterior corneal surface is crucial for assessing refractive surgery outcomes and safety.
  • Previous studies have focused more on anterior corneal changes, leaving posterior surface alterations less understood.

Purpose of the Study:

  • To quantify the frequency and nature of posterior corneal surface changes following photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK).
  • To compare these changes against natural variations in posterior corneal curvature over time in a control group.

Main Methods:

  • A nonrandomized, comparative trial involving 95 eyes (71 patients) undergoing PRK (45 eyes) or LASIK (50 eyes).

Related Experiment Videos

  • Posterior corneal curvature (PCC) was analyzed using elevation topography maps and compared between pre- and post-operative states.
  • Two analysis methods (float and apex-fixed best fit corneal curvature - ABC) were employed across various zone diameters, with comparisons to 70 non-surgery eyes.

    • Main Results:

    • Both PRK and LASIK groups exhibited flattening, steepening, and no significant change in PCC, with variations depending on the analysis method used.
    • For PRK, the float method showed 22.2% flattening, 53.3% no change, and 24.4% steepening; the ABC method showed 28.9% flattening, 35.6% no change, and 35.6% steepening.
    • For LASIK, the float method showed 20% flattening, 52% no change, and 28% steepening; the ABC method showed 30% flattening, 40% no change, and 30% steepening.
    • The non-surgery control group demonstrated similar degrees of PCC change over time, indicating natural variability.

    Conclusions:

    • The observed changes in posterior corneal curvature after PRK and LASIK were not statistically different from the natural variations seen in the control group.
    • This suggests that refractive surgery, within the parameters studied, does not induce significant, abnormal changes in the posterior corneal surface.
    • The findings support the safety profile of PRK and LASIK concerning posterior corneal biomechanics.