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Prunioside A: a new terpene glycoside from Spiraea prunifolia
1Professional Graduate School of Oriental Medicine, and Medicinal Resources Research Center, Wonkwang University, Iksan, Chonbuk 570-749, Republic of Korea.
Journal of Natural Products
|July 28, 2001
Abstract:
Prunioside A (1) has been isolated from an EtOAc-soluble extract of Spiraea prunifolia var. simpliciflora by a combination of chromatographic techniques. The structure was determined primarily by extensive NMR experiments. Compound 1 is a unique terpene glycoside. Its acetylated derivative (1a) inhibited nitric oxide production in murine macrophage-like RAW 264.7 cells in a dose-dependent manner.