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Developmental follow-up in 15-month-old infants of asthmatic vs. control mothers

M Schatz1, K Harden, M Kagnoff

  • 1Department of Allergy, Kaiser-Permanente Medical Center, 7060 Clairemeont Mesa Blvd., San Diego, CA 92111, USA. michael.x.schatz@kp.org

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
|July 28, 2001
PubMed

Insights

Infants born to mothers with well-managed asthma during pregnancy show similar mental and psychomotor development at 15 months compared to infants of non-asthmatic mothers. Active asthma management supports healthy infant neurodevelopment.

Area of Science:

  • Pediatrics
  • Neonatology
  • Neurodevelopmental Pediatrics

Background:

  • Maternal asthma during pregnancy can raise concerns about potential impacts on infant neurodevelopment.
  • Active management of asthma is crucial for maternal and fetal well-being.

Purpose of the Study:

  • To evaluate and compare mental and psychomotor development in infants of mothers with actively managed asthma versus infants of non-asthmatic mothers.
  • To identify factors influencing infant developmental outcomes.

Main Methods:

  • A cohort study assessed 379 infants of asthmatic mothers and 376 control infants at 15 months of age using the Bayley Scales of Infant Development.
  • Statistical analyses examined relationships between developmental indices and maternal asthma severity, socioeconomic status, and infant prematurity.

Main Results:

  • No significant differences in mental or psychomotor developmental indices were found between infants of asthmatic mothers and control infants.
  • Maternal asthma severity did not correlate with infant developmental outcomes.
  • Lower birth weight (<2,500g) was associated with lower psychomotor scores, and lower socioeconomic status with lower mental scores in both groups.

Conclusions:

  • Active asthma management during pregnancy leads to comparable infant developmental outcomes at 15 months of age.
  • Infant neurodevelopment is influenced by factors like birth weight and socioeconomic status, irrespective of maternal asthma status.
  • Effective prenatal asthma care supports positive infant neurodevelopmental trajectories.

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