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Lidocaine blood concentrations during fiberoptic bronchoscopy
The American Review of Respiratory Disease
|July 1, 1975
Summary
Lidocaine levels were measured in patients undergoing fiberoptic bronchoscopy. One patient showed toxic lidocaine concentrations, but most had safe levels, indicating potential risks in critically ill individuals.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Fiberoptic bronchoscopy frequently utilizes local anesthetics like lidocaine.
- Monitoring anesthetic drug levels is crucial for patient safety, especially in vulnerable populations.
Purpose of the Study:
- To assess blood lidocaine concentrations in patients undergoing fiberoptic bronchoscopy.
- To evaluate the safety and potential toxicity of lidocaine during this procedure.
Main Methods:
- Blood lidocaine concentrations were measured in 21 patients.
- Patients underwent routine fiberoptic bronchoscopy procedures.
Main Results:
- One patient exhibited lidocaine concentrations in the toxic range.
- Measurable but generally safe lidocaine levels were observed in the majority of patients.
Conclusions:
- Lidocaine adsorption can lead to cardiac and central nervous system toxicity, particularly in seriously ill patients.
- While toxicity was not observed in this study, careful monitoring is warranted.