In vitro evaluation of a new quinolone antibacterial

The activity of R-802, a quinolone antibacterial agent, was studied in vitro and found to be active against Enterobacteriaceae; less than 4 mug of drug per ml was required to inhibit most isolates. The majority of Pseudomonas aeruginosa grew in a concentration of 256 mug of R-802 per ml when studied in broth against an inoculum of 10(8) organisms per ml.