Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Anaphylaxis to celecoxib.

M B Levy1, J N Fink

  • 1Department of Pediatrics and Medicine, Medical College of Wisconsin, Milwaukee 53201, USA. mlevy@chw.org

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|July 31, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the basophil activation test and skin prick testing for the diagnosis of sesame food allergy.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2018
Same author

NUT Co Reactivity - ACquiring Knowledge for Elimination Recommendations (NUT CRACKER) study.

Allergy·2017
Same author

Changes in patient quality of life during oral immunotherapy for food allergy.

Allergy·2017
Same author

Clinical and laboratory 2-year outcome of oral immunotherapy in patients with cow's milk allergy.

Allergy·2015
Same author

Molecular biology and immunology of fungal allergens.

Indian journal of clinical biochemistry : IJCB·2012
Same author

The costimulatory molecules CD80, CD86 and OX40L are up-regulated in Aspergillus fumigatus sensitized mice.

Clinical and experimental immunology·2005
Same journal

Anaphylactic Shock Due to Contaminated Albuterol Nebulizer with an Asian Lady Beetle (Harmonia axyridis): A Case Report.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Associations between genetic ancestry and allergic outcomes at 10 years among Black children.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Five-Year Follow-up After Peach Sublingual Immunotherapy in LTP Syndrome.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Overlapping Mechanisms and Novel Biomarkers Define Asthma and COPD as a Spectrum of Airway Disease.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Real-World Variation in Post-Dose Supervision and Activity Restriction During Maintenance Cow's Milk Oral Immunotherapy.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
Same journal

Small Airway Dysfunction and Prior Exacerbations are Common in Primarily Well-Controlled Pediatric Asthma.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2026
See all related articles

This report details a rare case of anaphylaxis, a severe allergic reaction, to celecoxib, a nonsteroidal anti-inflammatory drug (NSAID). Healthcare providers should monitor patients for potential serious side effects of this medication.

Area of Science:

  • Pharmacology
  • Immunology
  • Clinical Medicine

Background:

  • Nonsteroidal anti-inflammatory agents (NSAIDs) are associated with adverse reactions including urticaria, angioedema, asthma, and anaphylaxis.
  • Celecoxib is a novel NSAID with a distinct structure and mechanism of action compared to other drugs in its class.

Observation:

  • A 55-year-old woman presented with acute pruritus, urticaria, respiratory distress, and hypotension shortly after taking a celecoxib capsule.
  • The patient had previously tolerated celecoxib without issue when treated for tendonitis.

Findings:

  • The patient experienced a severe anaphylactic reaction following celecoxib ingestion.
  • Treatment with epinephrine, corticosteroids, and intravenous fluids resulted in successful recovery.
  • An IgE-mediated mechanism for the reaction could not be identified.

Related Experiment Videos

Implications:

  • This case represents the first reported instance of anaphylaxis attributed to celecoxib.
  • Healthcare professionals must remain vigilant regarding the potential for serious adverse reactions to this new NSAID.
  • Awareness of celecoxib's potential side effects is crucial for patient safety.