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Updated: Aug 8, 2026

Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Optic disk edema as a presentation of Propionibacterium acnes endophthalmitis
G A Kouyoumdjian1, T P Larkin, P J Blackburn
1Department of Ophthalmology, University of Colorado Health Sciences Center, Denver 80262, USA. gregory.kouyoumdjian@uchsc.edu
Purpose:
To report a patient with an initial presentation of optic disk edema secondary to Propionibacterium acnes endophthalmitis.
Methods:
Interventional case report. The patient had surgery and treatment related to endophthalmitis. Nine months after cataract surgery with posterior chamber lens implant, a 79-year-old man receiving topical corticosteroids in the same eye presented with best-corrected visual acuity of 20/60, a superior visual field defect, and optic nerve edema without intraocular inflammation. One year postoperatively, the eye presented a further decrease in best-corrected visual acuity, and a dense white plaque was noted on the posterior capsule.
Results:
One year postoperatively, a partial capsulectomy with vitrectomy and injection of intravitreal antibiotics was performed. Hematoxylin and eosin stain of the posterior capsule plaque revealed gram-positive coccobacilli characteristic of P. acnes.
Conclusion:
Propionibacterium acnes endophthalmitis may present after cataract surgery with intraocular lens implant with decreased vision, optic disk edema, and a visual field defect.
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