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[Clinical study on relationship among Heart-Qi Deficiency, left ventricular function and myocardial ischemia in

S Wang1, M Zhao, X Lu

  • 1Dongzhimen Hospital, Beijing University of TCM, Beijing 100700.

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine
|August 2, 2001
PubMed

Insights

Heart-Qi Deficiency (HQD) is linked to impaired left ventricular function in coronary heart disease (CHD) patients. Chinese herbal medicine effectively improves cardiac function and reduces myocardial ischemia in these patients.

Area of Science:

  • Cardiology
  • Traditional Chinese Medicine

Background:

  • Coronary heart disease (CHD) is a significant health concern.
  • Heart-Qi Deficiency (HQD) is a pattern observed in Traditional Chinese Medicine (TCM) that may be associated with CHD.
  • Understanding the relationship between HQD, cardiac function, and myocardial ischemia is crucial for effective treatment.

Purpose of the Study:

  • To investigate the association between Heart-Qi Deficiency (HQD) and left ventricular function in patients with coronary heart disease (CHD).
  • To evaluate the role of HQD in myocardial ischemia.
  • To assess the therapeutic effects of Radix Codonopsitis Pilosulae on left ventricular function and myocardial ischemia in CHD patients.

Main Methods:

  • Utilized Doppler echocardiogram and electrocardiogram to assess 103 clinically diagnosed CHD patients.
  • Included patients with stable angina pectoris, treated with either Radix Codonopsitis Pilosulae or Nifedipine.

Main Results:

  • Left ventricular systolic and diastolic function insufficiency was more prevalent in CHD patients with HQD compared to those without.
  • Left ventricular diastolic function demonstrated 87% susceptibility, and systolic function showed 88% specificity for evaluating HQD.
  • Radix Codonopsitis Pilosulae treatment was observed to protect left ventricular function and alleviate myocardial ischemia.

Conclusions:

  • Myocardial ischemia and blood stasis are identified as causes of HQD.
  • Treatment of HQD with Chinese herbal medicine, specifically Radix Codonopsitis Pilosulae, can effectively improve blood stasis and reduce myocardial ischemia.
  • The therapeutic mechanism may involve enhancing cardiac muscle diastolic and systolic function, reducing resistance pressure, and maintaining coronary perfusion pressure to improve heart blood supply.
Abstract

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