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[Salvia Miltiorrhizae Composita in preventing PaO2 lowering induced by controlled hypotension with nitroglycerin]
1Department of Anesthesiology, First Affiliated Hospital of Hubei Medical University, Wuhan 430060.
Objective:
To observe the effects of Salvia Miltiorrhizae Composita (SMC) on blood gas variations of nitroglycerin (NTG) controlled hypotension.
Methods:
Sixteen patients who were arranged to undergo operation under general anesthesia in controlled hypotension condition were divided randomly into control group (n = 8) and SMC group (treated group, n = 8), NTG were used to create controlled hypotension in both groups and blood pressure decrease about 30% comparing with the control values. Patients in the treated group were administered intravenously with SMC (16 ml) before the utilization of NTG.
Results:
Significant PaO2 decrease and Pa-etCO2 increase were observed in the control group during the controlled hypotension period. However, blood gas values in the treated group did not evidently change.
Conclusion:
It suggested that SMC can prevent the side effects of NTG on blood gas.
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