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Published on: June 29, 2013
Haemodynamic, invasive and echocardiographic monitoring in the hypertensive parturient
1North Staffordshire Maternity Unit, Newcastle Road, Stoke on Trent, Staffs, ST4 6QG, UK.
Insights
This review found no randomized trials on the clinical usefulness of invasive (pulmonary artery catheters) or non-invasive (echocardiography) hemodynamic assessments in pre-eclampsia. Data on hemodynamic profiles exist, but clinical impact remains unclear.
Area of Science:
- Obstetrics and Gynecology
- Cardiology
- Critical Care Medicine
Background:
- Pre-eclampsia is a serious hypertensive disorder unique to pregnancy.
- Hemodynamic assessment is crucial for managing severe pre-eclampsia.
- The clinical utility of various hemodynamic monitoring techniques in pre-eclampsia remains debated.
Purpose of the Study:
- To systematically review the literature on the clinical usefulness of invasive and non-invasive hemodynamic assessments in pre-eclampsia.
- To evaluate the evidence supporting the use of pulmonary artery catheters and echocardiography in this patient population.
Main Methods:
- A comprehensive systematic literature review was conducted.
- MEDLINE database search using MESH headings and textwords.
- Screening of over 1500 abstracts, followed by full-text review of 156 papers, with 55 yielding relevant data.
Main Results:
- No randomized controlled trials were identified that demonstrate the clinical usefulness of pulmonary artery catheters or echocardiography in hypertensive pregnancy.
- Extensive data exist on the hemodynamic profiles of women with pre-eclampsia.
- A poor correlation was observed between right and left heart filling pressures, with unclear clinical impact.
Conclusions:
- Current evidence does not support the routine clinical use of invasive or non-invasive hemodynamic monitoring for guiding management in pre-eclampsia.
- Further research, particularly randomized controlled trials, is needed to establish the clinical value of these assessments.
Aim:
To determine the clinical usefulness of invasive and non-invasive haemodynamic assessment in pre-eclampsia.
Method:
A systematic review of the literature was undertaken, using a MEDLINE electronic search using a combination of MESH headings and textwords. Over 1500 abstracts were perused; we obtained 156 full papers that were related to the subject matter. Of the full papers, 55 yielded relevant information. Hand-searching the reference lists of the retrieved papers completed the search.
Results:
There are no data from randomized controlled clinical trials illustrating the clinical usefulness of pulmonary artery catheters or echocardiographic techniques in hypertensive pregnancy. There are a wealth of data illustrating the haemodynamic profiles of both untreated and treated pre-eclamptic women. Data are also available comparing right heart and left heart filling pressures, demonstrating a relatively poor correlation between the two values. The clinical impact of either measurement is unclear. Data are available illustrating the correlation between echocardiographic techniques and pulmonary artery catheterization.
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