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Related Experiment Videos

Tetanus. A clinical review.

J M Al-Kaabi1, E M Scrimgeour, A Louon

  • 1Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman. drkaabi@hotmail.com

Saudi Medical Journal
|August 2, 2001
PubMed
Summary

Tetanus remains an infrequent but serious disease in Oman, requiring intensive care. Early diagnosis and multidisciplinary management contributed to a 10% mortality rate in this study.

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Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Public Health

Background:

  • Tetanus, though uncommon in Oman due to immunization programs, still presents sporadically.
  • Global mortality rates for tetanus remain high, emphasizing the disease's severity.
  • Patients at Sultan Qaboos University Hospital require extensive Intensive Care Unit (ICU) stays and multidisciplinary care.

Purpose of the Study:

  • To evaluate the outcomes of tetanus patients treated at Sultan Qaboos University Hospital over a decade.
  • To assess the effectiveness of aggressive, multidisciplinary management in reducing tetanus mortality.

Main Methods:

  • Retrospective review of all tetanus cases admitted between 1991 and 1999.
  • Analysis of patient demographics, clinical presentation, ICU treatment protocols, and outcomes.
  • Focus on early diagnosis and coordinated multidisciplinary management strategies.

Main Results:

  • Ten cases (9 adults, 1 infant) were identified, with adults averaging 59 years old.
  • All patients presented with severe generalized tetanus, requiring prolonged ICU care (average 5.5 weeks for survivors).
  • The overall mortality rate was 10%, with one adult death and a surviving infant.

Conclusions:

  • Tetanus in Oman is rare but necessitates prolonged, intensive, and costly treatment.
  • The study achieved a comparatively low mortality rate (10%) attributed to early diagnosis, aggressive treatment, and multidisciplinary care.
  • Effective management strategies are crucial for improving outcomes in severe tetanus cases.

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