Related Experiment Video
Updated: Oct 5, 2026

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
Published on: April 3, 2026
[Possibilities for surgical treatment of locally spread head and neck cancer]
Abstract:
The results of treatment of 263 patients with locally spread cutaneous cancer of head and neck, lower lip, the oral cavity mucosa, larynx and thyroid gland, to whom 299 surgical interventions were done, including 121 radical excision of cervical fat with prophylactic and curative aim, were analyzed. There were admitted to hospital 187 (71.1%) patients with III stage of the disease 41 (15.6%)--in IVa stage, with tumor recurrency--35 (13.3%). Common postoperative complications occurred in 19 (7.2%) patients and the local--in 83 (31.6%). The best 5-year survival indexes were noted in cutaneous and thyroid gland cancer (69.8 and 70.5% accordingly); the poorest--in cancer of the oral cavity mucosa (39.7%); in cancer of lower lip and of larynx--52.9 and 61.3%.
