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Five-year mortality in men and women with atrial fibrillation
1The Husläkarna i Osteråker Health Centre, Akersberga, Sweden.
Objective:
Five-year mortality in men and women with atrial fibrillation (AF).
Design:
A follow-up of the medical records of patients with AF registered on September 30, 1993.
Setting:
One community health centre in Stockholm County.
Subjects:
129 patients (76 men and 53 women).
Main Outcome Measures:
Observed and expected, age- and sex-standardised, 5-year mortality rates. Significant risk factors by multiple logistic regression.
Results:
Women had a higher mean age (77.5 vs 72.8 years) and more often suffered from heart failure and hypothyreosis. Five-year mortality rate for men was 30% vs expected 27% in Sweden and 24% in the community; for women it was 43% vs expected 29% (p <0.05) and 23% in the community (p < 0.001), i.e. an excess mortality of 49% and 88%, respectively. Significant factors predicting death by logistic regression among women were: age (odds ratio 1.39, p < 0.001), levothyroxine treatment (odds ratio 27.87, p < 0.05) and diabetes (odds ratio 20.75, p < 0.05).
Conclusions:
AF is related to an excess sex- and age-standardised, 5-year mortality in women but not in men, with levothyroxine treatment as one significant factor.