Related Experiment Video

Updated: Jul 28, 2026

Single-step Purification of Macromolecular Complexes Using RNA Attached to Biotin and a Photo-cleavable Linker
08:12

Single-step Purification of Macromolecular Complexes Using RNA Attached to Biotin and a Photo-cleavable Linker

Published on: January 3, 2019

Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing

M Puttaraju1, J DiPasquale, C C Baker

  • 1Intronn LLC, 840 Main Campus Drive, Raleigh, North Carolina 27606, USA.

Molecular Therapy : the Journal of the American Society of Gene Therapy
|August 3, 2001
PubMed

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Splicing is the process by which eukaryotic RNA is edited before its translation into protein. The RNA strand transcribed from eukaryotic DNA is called the primary transcript. The primary transcripts that become mRNAs are called precursor messenger RNAs (pre-mRNAs). Eukaryotic pre-mRNA contains alternating sequences of exons and introns. Exons are nucleotide sequences that code for proteins, whereas introns are the non-coding regions. In RNA splicing, introns are removed and exons are bonded...
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