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Psychotropic medication in children: a study from the Netherlands.

E Schirm¹, H Tobi, J M Zito

¹Groningen Institute for Drug Exploration (GUIDE), University of Groningen, University Centre for Pharmacy, Section of Social Pharmacy and Pharmacoepidemiology, Groningen, The Netherlands.

|August 3, 2001

Summary

Psychotropic medication use in Dutch children is lower than in the US, but stimulant use is increasing. This rise in stimulant prescriptions mirrors trends seen in the United States, indicating a broader pattern.

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Area of Science:

Pediatric pharmacology
Drug utilization studies
Child and adolescent psychiatry

Background:

Global concern exists regarding increased psychotropic agent use in children.
Existing research primarily originates from the US, often using data from the mid-1990s.
Few studies comprehensively document the use of diverse psychotropic agent types in pediatric populations.

Purpose of the Study:

To investigate psychotropic medication utilization in children and adolescents in the Netherlands.
To compare Dutch psychotropic drug use patterns with previously reported US figures.
To analyze trends in the use of specific psychotropic agent classes.

Main Methods:

A drug utilization study was conducted using computerized pharmacy dispensing records.
The study period spanned from 1995 to 1999.
The research focused on children aged 0 to 19 years in the northern Netherlands.

Main Results:

Stimulants were the most prevalent psychotropic agents (7.4/1000 in 1999), followed by hypnotics/anxiolytics (6.9/1000) and antidepressants (4.4/1000).
Prevalence of stimulant use significantly increased from 1.5/1000 in 1995 to 7.4/1000 in 1999.
Most children (vast majority) received only one psychotropic agent concurrently.

Conclusions:

The prevalence of stimulant use in the Netherlands is considerably lower than US figures from 1995 (28/1000).
Differences were observed in the use of other psychotropic agents and their combinations compared to US data.
The observed increase in Dutch stimulant use aligns with US trends, suggesting this is not a US-exclusive phenomenon.