Related Experiment Videos
Greasing the wheels of secretory transport
1Division of Biochemistry and Molecular Biology of the Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202 USA. jeremy@socrates.berkeley.edu
Nature Cell Biology
|August 3, 2001
Abstract:
Ever since George Palade's pioneering studies of zymogen secretion from pancreatic acinar cells, the underlying molecular mechanisms of vesicle-mediated protein transport have captivated cell biologists and biochemists. A watershed meeting on "Phosphoinositides and the Golgi", held at the Fogarty International Center of the National Institutes of Health in Bethesda, Maryland (March 13-14, 2001), provided reinterpretation and striking new insights about the functions of this phospholipid class in intracellular protein trafficking.