Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Immunization for children treated for solid tumors: what are the guidelines?].

P Marec-Bérard1, D Floret, M Schell

  • 1Département d'oncologie pédiatrique, centre Léon-Bérard, 28, rue Laënnec, 69373 Lyon, 08, France. marec@lyon.fnclcc.fr

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|August 4, 2001
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of women with abnormal cervical cytology: Update of French guidelines after the implementation of HPV screening.

European journal of obstetrics, gynecology, and reproductive biology·2025
Same author

[Vaccines and vaccination against human papillomaviruses in 2008].

Virologie (Montrouge, France)·2022
Same author

Fifty years of clinical and research studies for childhood renal tumors within the International Society of Pediatric Oncology (SIOP).

Annals of oncology : official journal of the European Society for Medical Oncology·2021
Same author

Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways.

Cell death discovery·2020
Same author

Clinical management of adolescents and young adults suffering from sarcoma in the French Rhône-Alpes region: A prospective exhaustive cohort with 10 years follow up.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2020
Same author

[The development of vaccination policy].

Revue des maladies respiratoires·2019

Children undergoing chemotherapy for solid tumors should delay most immunizations. Guidelines suggest waiting 3-6 months post-chemotherapy for routine vaccines and up to 12 months for certain boosters, with exceptions for specific conditions.

Area of Science:

  • Pediatric Oncology
  • Immunology
  • Vaccinology

Context:

  • Chemotherapy (CT) for solid tumors can impact a child's immune system, leading to uncertainty regarding appropriate vaccination schedules.
  • Lack of consensus exists on the optimal timing for immunizations in pediatric cancer patients undergoing CT.

Purpose:

  • To establish evidence-based guidelines for childhood immunization during and after chemotherapy treatment for solid tumors.
  • To provide recommendations on vaccine administration timing based on CT intensity and patient age.

Summary:

  • Most vaccines are contraindicated during chemotherapy, with hepatitis B vaccine being a potential exception.
  • A 3-month post-CT interval is recommended before initiating new vaccinations or boosters for diphtheria, tetanus, polio, pertussis, and Haemophilus influenzae type b in children under 5.

Related Experiment Videos

  • A 6-month interval is advised for live vaccines (mumps, measles, rubella) if initial immunization or revaccination is needed and serology is negative.
  • Following high-dose CT, a 12-month interval and normalized lymphocyte count are required before boosters, with antibody titers checked.
  • Varicella vaccination is not routinely recommended; pneumococcal vaccine is advised for asplenic patients. Other vaccines require individual assessment.

    • Impact:

    • Provides clear guidance for clinicians managing pediatric cancer patients, improving vaccine safety and efficacy.
    • Aims to optimize long-term immune protection for survivors of childhood solid tumors.
    • Facilitates standardized vaccination protocols in pediatric oncology settings.