Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Invasive pneumococcal infection in children.

C H Yu1, N C Chiu, F Y Huang

  • 1Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan. ncc88@ms2.mmh.org.tw

The Southeast Asian Journal of Tropical Medicine and Public Health
|August 4, 2001
PubMed
Summary

Invasive pneumococcal infections in children, particularly meningitis, are linked to poor outcomes and rising penicillin resistance. Early antibiotic treatment is crucial for better results in pediatric cases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Advances in research on metabolic associated fatty liver disease in 2025].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2026
Same author

Associations of socioeconomic status and malnutrition with survival in adults with cancer in the UK Biobank: A prospective cohort study.

Public health·2025
Same author

Traffic-related air pollution, chronic stress, and changes in exhaled nitric oxide and lung function among a panel of children with asthma living in an underresourced community.

The Science of the total environment·2023
Same author

[Effects of tensile force on the vascular lumen formation in three-dimensional printed tissue].

Zhonghua shao shang yu chuang mian xiu fu za zhi·2023
Same author

[MDT management of nonalcoholic fatty liver disease].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2023
Same author

[Comparison of the efficacy of thulium fiber laser and holmium laser lithotripsy in the treatment of upper urinary tract stones].

Zhonghua yi xue za zhi·2023

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcus pneumoniae infections pose significant mortality and morbidity risks, affecting multiple organs.
  • Invasive pneumococcal infections are a serious concern in pediatric populations.
  • Previous studies highlight the need to understand trends in pediatric pneumococcal disease.

Purpose of the Study:

  • To review invasive pneumococcal infections in children treated at a Taipei teaching hospital from 1984 to 1998.
  • To identify risk factors, clinical presentations, and outcomes associated with pediatric invasive pneumococcal disease.
  • To analyze trends in antibiotic resistance, specifically penicillin resistance, over the study period.

Main Methods:

  • Retrospective review of 81 pediatric patients hospitalized with invasive pneumococcal infection.

Related Experiment Videos

  • Data collection included patient demographics, clinical manifestations, infection sites, and outcomes.
  • Statistical analysis, including multi-regression, was used to identify factors affecting prognosis and antibiotic resistance patterns.

    • Main Results:

    • The majority of patients (81.7%) were under 5 years old, with infections peaking from October to March.
    • Common presentations included sepsis (60), meningitis (28), pneumonia with pleural effusion (27), and arthritis (4), with 38 patients having multiple infection sites.
    • Mortality was 16.0% and severe sequelae occurred in 24.7%; meningitis and complications independently predicted poor outcomes.
    • Penicillin-resistant strains increased significantly from 1990 onwards, comprising four-fifths of infections in the final two study years.

    Conclusions:

    • Invasive pneumococcal infections in children carry a substantial risk of poor prognosis and severe sequelae.
    • The rising prevalence of penicillin-resistant Streptococcus pneumoniae strains necessitates careful consideration of antibiotic strategies.
    • Prompt and appropriate antibiotic therapy is essential for improving outcomes in pediatric patients with invasive pneumococcal infections.