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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Compliance with secondary prevention of ischemic stroke: a prospective evaluation

T Sappok1, A Faulstich, E Stuckert

  • 1Department of Neurology, Stroke Unit, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin, Germany.

Stroke
|August 4, 2001
PubMed

Insights

Patient compliance with secondary stroke prevention medication is good one year after ischemic stroke. Older age, greater stroke severity, and cardioembolic stroke predict better adherence to antithrombotic and risk factor treatments.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Secondary prevention of ischemic stroke relies on patient adherence to pharmacological therapies.
  • Limited data exist on patient compliance outside clinical trials for antithrombotic and risk factor treatments.
  • Understanding compliance is crucial for effective stroke prevention strategies.

Purpose of the Study:

  • To assess the rate of patient compliance with secondary stroke prevention 1 year after cerebral ischemia.
  • To identify predictors of compliance with antithrombotic and risk factor medications.
  • To determine reasons for noncompliance in stroke patients.

Main Methods:

  • Prospective recruitment of patients with ischemic stroke or TIA on antithrombotic medication.
  • Structured telephone interviews at 1 year to evaluate compliance with antithrombotic and risk factor medications.
  • Logistic regression analysis to identify independent predictors of compliance.

Main Results:

  • At 1 year, 87.6% of patients remained on antithrombotic medication, and 70.2% were on the same agent.
  • Compliance rates for hypertension, diabetes, and hyperlipidemia treatment were 90.8%, 84.9%, and 70.2%, respectively.
  • Older age, higher stroke severity on admission, and cardioembolic stroke cause were significant predictors of compliance.

Conclusions:

  • Compliance with secondary stroke prevention is generally good 1 year post-ischemic stroke in this study cohort.
  • Factors associated with better long-term compliance include advanced age, severe neurological deficits, and cardioembolic stroke etiology.
  • Identifying compliance determinants can guide interventions to enhance stroke prevention quality.
Abstract

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