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Studies of the complexation of chloranilic acid with proguanil
M U Adikwu1, P F Builders, K C Ofokansi
1Department of Pharmaceutics, Faculty of Pharmaceutical Sciences-University of Nigeria, Nsukka, Nigeria.
Bollettino Chimico Farmaceutico
|August 7, 2001
Abstract:
Studies on the complexation between chloranilic acid and proguanil has been carried out. The chloranilic acid acted as a pi-electron donor. The stoichiometric relationship in the complex was determined by employing the Job's method of continuous variation. The results indicate that the complex exhibits a purple colour and absorbs maximally at 520 nm. Spectrophotometric studies show that the method could be useful in the analysis of proguanil.