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Related Experiment Videos

New guidelines for managing hypercholesterolemia.

J M McKenney1

  • 1School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, and National Clinical Research, Richmond 23294, USA. jmckenney@ncrinc.net

Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|August 7, 2001
PubMed
Summary
This summary is machine-generated.

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Pharmacotherapy of dyslipidemia.

Cardiovascular drugs and therapy·2002

Pharmacists can improve hyperlipidemia management by applying the National Cholesterol Education Program

Area of Science:

  • Cardiovascular Medicine
  • Pharmacology
  • Public Health

Background:

  • Hypercholesterolemia management guidelines are crucial for reducing coronary heart disease (CHD) risks.
  • The National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) provides updated recommendations.

Purpose of the Study:

  • To summarize the NCEP ATP III guidelines for pharmacists.
  • To outline a practical approach for pharmacists in managing hypercholesterolemia.

Main Methods:

  • Review of the NCEP ATP III executive summary.
  • Inclusion of pertinent literature identified by the author.

Main Results:

  • ATP III emphasizes lowering low-density lipoprotein cholesterol (LDL-C) to <100 mg/dL and managing high triglycerides (>200 mg/dL).

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  • Guidelines highlight identifying patients at high risk for CHD events.
  • A six-step process is recommended for pharmacists: lipid profile assessment, CHD risk categorization, goal setting, lifestyle changes, LDL-C lowering therapy, and consideration of other lipid factors.

    • Conclusions:

    • Many patients discontinue lipid-lowering therapy within a year, with low goal attainment rates.
    • NCEP ATP III guidelines offer pharmacists an opportunity to enhance pharmaceutical care for hyperlipidemia patients.