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Related Experiment Videos

Formaldehyde release from ground root canal sealer in vitro.

M J Koch1, E Wünstel, G Stein

  • 1Poliklinik für Zahnerhaltungskunde, Ruprecht-Karls-University, Heidelberg, Germany.

Journal of Endodontics
|August 7, 2001
PubMed
Summary

Formaldehyde release from ground root canal sealers AH26, Amubarut, and N2 was measured. While generally low, N2 showed significantly less formaldehyde release than AH26 and Amubarut.

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Area of Science:

  • Dental Materials Science
  • Endodontics
  • Toxicology

Background:

  • Root canal sealers are crucial in endodontic therapy.
  • Formaldehyde release from sealers can pose potential risks.
  • Understanding sealer material properties is vital for patient safety.

Purpose of the Study:

  • To quantify formaldehyde release from three ground root canal sealer materials: AH26, Amubarut, and N2.
  • To compare the formaldehyde release levels among these sealers.
  • To assess the potential risk of allergic reactions due to formaldehyde.

Main Methods:

  • Specimens of AH26, Amubarut, and N2 were ground and stored dry for 6 months.
  • Ground material (100-200 mg) was immersed in distilled water for 10 minutes.

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  • Formaldehyde concentration in immersion water was determined using high-performance liquid chromatography (HPLC).

    • Main Results:

    • Mean formaldehyde release per mg material: AH26 (6.6 ± 2.5 µg), Amubarut (8.3 ± 1.0 µg).
    • N2 samples exhibited significantly lower formaldehyde release (0.3 ± 0.1 µg/g; p < 0.0001).
    • Formaldehyde release from all tested ground root canal materials was found to be low.

    Conclusions:

    • Formaldehyde release from ground root canal sealers is generally low.
    • N2 demonstrates a significantly lower formaldehyde release compared to AH26 and Amubarut.
    • Despite low levels, the potential for allergic reactions in susceptible patients cannot be entirely ruled out.