Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at

Z Yang1, X Qu, C Y Yu

  • 1Children's Research Institute, 700 Children's Drive, Columbus, Ohio 43205-2664, USA. zhenyu.yang@menlo.ppdi.com

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Protein Complexes with Interchangeable Parts

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Position-effect Variegation

In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
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