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Updated: Oct 5, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
The VO(2) response at the onset of severe intensity exercise
1Department of Kinesiology, University of North Texas, Denton, TX 76203, USA.
Abstract:
Fourteen participants achieved a peak VO(2) of 2573 +/- 738 ml á min-1 in approximately 3 1/2-min cycle ergometer tests. However, in the first 45 s of exercise, formal description of the phase II of the V(O)2 response indicated that the V(O)2 was projecting toward a value of 3451 +/- 1599 ml x min(-1), well above the peak VO(2)peak and not different from the predicted O(2) demand of 3389 +/- 800 ml x min(-1). We conclude that, at the onset of exercise in the severe intensity domain, VO(2) is initially driven toward the O(2) demand, and then is limited by the achievable VO(2) (VO(2peak)).
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