Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Healthcare Associated Infections II: Preventive Measures

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

Endocarditis III: Medical Management

Endocarditis III: Medical Management

Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...

Microorganisms in Medicine and Therapeutics

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.

Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

Clinical Significance of Antibiotic Resistance

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Not Available].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·2016

Same author

[Comments on the PREFERE study].

Der Urologe. Ausg. A·2015

Same author

[PREFERE--the German prostatic cancer study].

Der Urologe. Ausg. A·2013

Same author

[What is the benefit of mammography? -- mammography screening: careful consideration required].

Deutsche medizinische Wochenschrift (1946)·2013

Same author

[Validity of Recommendations for Secondary Prevention of Colon Cancer].

Zentralblatt fur Chirurgie·2013

Same author

[Clinical economics: a concept to optimize healthcare services].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2012

Search research articles

Related Experiment Video

Updated: Jul 12, 2026

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

Published on: February 11, 2011

[Evidence-based medicine in ENT].

F Porzsolt¹, A Ohletz

¹AG Klinische Okonomik, Universitätsklinikum Ulm.

Laryngo- Rhino- Otologie

|August 8, 2001

Summary

This summary is machine-generated.

This study explores why some clinicians dislike Evidence-Based Medicine (EBM) and outlines six steps for its practical application to solve clinical problems and improve patient care.

More Related Videos

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion

Published on: July 3, 2026

Related Experiment Videos

Last Updated: Jul 12, 2026

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

Published on: February 11, 2011

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates

Published on: February 17, 2023

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion

Amikacin Protection Assay for Quantification and Visualization of Escherichia coli Cell Invasion

Published on: July 3, 2026

Area of Science:

Clinical Practice
Medical Education

Background:

Some healthcare professionals associate negative feelings with Evidence-Based Medicine (EBM).
Understanding and overcoming these negative associations is crucial for effective clinical practice.

Purpose of the Study:

To address the reasons behind negative perceptions of EBM.
To demonstrate the practical utility of EBM in solving daily clinical challenges.
To provide a structured approach for implementing EBM in clinical settings.

Main Methods:

A clinical example is used to illustrate the concepts.
The six formal steps for EBM implementation are detailed.
The process involves formulating questions, assessing internal and external evidence, critical appraisal, integration, and outcome evaluation.

Main Results:

EBM can effectively address day-to-day clinical problems.
A clear, six-step process facilitates EBM integration.
The steps guide clinicians from problem identification to patient benefit assessment.

Conclusions:

Addressing negative perceptions of EBM is important.
The six-step implementation framework supports the practical application of EBM.
Successful EBM integration leads to improved patient outcomes.