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[Cortinarius poisoning. Analysis of cases in the literature]
1Unité de toxicologie clinique, Département pluridisciplinaire de médecine, Centre hospitalier universitaire de Grenoble. Psaviuc@chu-grenoble.fr
Unlabelled:
Cortinarius spp. poisoning is characterized by a delayed acute renal failure (ARF). The main features of this severe poisoning are still poorly known and often overlooked. The aim of this review of the literature was a better description of Cortinarius spp. poisoning.
Methods:
The main medical databases were searched and analysed.
Results:
245 cases were collected and 90 cases could be analysed in details. Gastrointestinal disorders appeared a few days after the ingestion of the mushrooms (median: three days). The renal phase is delayed (median: 8.5 days). Hepatic failure and muscular lesions are highly questionable. Treatment is supportive in half of the cases, ARF progressed towards chronic renal failure, which progressed in 70% of the cases towards terminal renal failure.
Conclusion:
Cortinarius spp. poisoning is severe. Ingestion of Cortinarius species must be systematically suspected whenever tubulo-interstitial nephritis is diagnosed.
