Related Experiment Videos
Inducible nitric oxide synthase and Salmonella infection
1Mucosal Immunology Laboratory, Combined Program in Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA. cherayil@helix.mgh.harvard.edu
Microbes and Infection
|August 8, 2001
Abstract:
Salmonella infection is associated with the increased expression of inducible nitric oxide synthase in macrophages and other cells. This review summarizes current knowledge of the molecular mechanisms involved in the induction process, and discusses the functional significance of nitric oxide production in the context of host defense against Salmonella.