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Updated: Jul 27, 2026

Vein Interposition Model: A Suitable Model to Study Bypass Graft Patency
Published on: January 15, 2017
Aortic graft infections: replacement with autogenous vein
1Division of Vascular Surgery, Department of Surgery, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9157, USA. james.valentine@utsouthwestern.edu
Superficial femoral-popliteal vein (SFPV) replacement of infected aortic prostheses offers a durable, infection-resistant solution. This method achieves low mortality and amputation rates, making it a viable alternative for complex cases.
Area of Science:
- Vascular Surgery
- Infectious Disease Management
- Prosthetic Graft Complications
Background:
- Aortic graft infections pose significant challenges in vascular surgery.
- Traditional treatments like graft excision and extra-anatomic bypass have limitations.
- The need for infection-resistant and durable graft materials is critical.
Purpose of the Study:
- To review and summarize institutional experience using the superficial femoral-popliteal vein (SFPV) for aortic prosthesis replacement.
- To evaluate the efficacy and safety of SFPV in treating infected aortic grafts.
Main Methods:
- Review of published experience utilizing SFPV for infected aortic prostheses.
- Single-stage SFPV bypass and prosthetic graft excision procedure.
- Analysis of operative times, mortality, amputation rates, and long-term outcomes.
Main Results:
- SFPV demonstrates high resistance to all types of infections.
- No long-term degeneration of the SFPV has been observed.
- Associated with low mortality and amputation rates, superior to alternative methods.
Conclusions:
- Graft excision and replacement with SFPV is an excellent alternative for aortic graft infections.
- SFPV is particularly suitable for complex aortofemoral reconstructions when extra-anatomic bypass is not feasible.
- Minimal venous sequelae result from SFPV harvest.
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