Evaluation of University of Florida split-course technique for various head and neck squamous cell carcinomas

A retrospective evaluation was made of 260 patients with squamous carcinoma of various head and neck sites in order to determine the relative value of continuous vs. split-course irradiation techniques. There was no obvious difference in local control or survival in early-stage cases. The continuous technique resulted in a better local control and survival rate in moderately advanced and advanced stages. Complications were less severe in the split-course cases.