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Related Experiment Videos

Meigs' Syndrome: Dr. Richard Cabot's Hidden First American Case.

Robert H. Young1

  • 1James Homer Wright Pathology Laboratories of the Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

International Journal of Surgical Pathology
|August 9, 2001
PubMed
Summary

Meigs' syndrome, characterized by ovarian tumors, ascites, and pleural effusion, was described in 1937. Earlier reports of this association existed, including one by Dr. Richard C. Cabot in 1912.

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Area of Science:

  • Gynecologic Pathology
  • Pulmonary Medicine
  • Medical History

Background:

  • Meigs' syndrome, a triad of ovarian fibroma, ascites, and pleural effusion, was popularized by Meigs and Cass in 1937.
  • Historical accounts indicate earlier observations of this association.
  • The contributions of prior researchers to the understanding of Meigs' syndrome are significant.

Purpose of the Study:

  • To trace the historical origins and attribution of Meigs' syndrome.
  • To highlight the contributions of Dr. Richard C. Cabot to the understanding of Meigs' syndrome.
  • To provide a comprehensive review of the literature preceding the 1937 report.

Main Methods:

  • Literature review of medical publications.
  • Historical case analysis.

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  • Biographical research on key medical figures.

    • Main Results:

    • Dr. Joe V. Meigs and Dr. John W. Cass described Meigs' syndrome in 1937.
    • Dr. Meigs acknowledged earlier literature in later writings.
    • Dr. Richard C. Cabot reported a similar case in 1912, which was not cited by Meigs and Cass.

    Conclusions:

    • The attribution of Meigs' syndrome requires careful historical consideration.
    • Dr. Cabot's 1912 report represents an important early description of the syndrome.
    • Accurate citation of prior work is crucial in medical literature.