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Melanotic Neuroectodermal Tumor of Infancy: Clinicopathologic Study of a Case, with Emphasis on the Chemotherapeutic
Roberto J. V. Mello1, Aurora K. L. Vidal, Horácio M. Fittipaldi
1Department of Pathology, Cancer Hospital of Pernambuco/Department of Pathology, Federal University of Pernambuco.
Abstract:
A case of melanotic neuroectodermal tumor of infancy (MNTI) in a 6-months-old white female child is presented. The tumor was located in the left half of the superior maxillary bone and affected the maxillary sinus, inducing large facial asymmetry. The histologic aspects of the tumor were typical for the entity: two cell populations, one pigmented melanocyte-like cell, the other small neuroblastic-like cell. After adjuvant chemotherapeutic treatment with a strong reduction of the tumor, the melanocyte-like cell predominated, allowing a better result of the surgery and probably a better prognosis. Int J Surg Pathol 8(3):247-251, 2000