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Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia
Published on: June 26, 2020
Approaches to reduce neurologic complications during cardiac surgery
J W Hammon1, D A Stump, J B Butterworth
1Department of Cardiothoracic Surgery, Wake Forest University School of Medicine, Winston-Salem, NC, USA. jhammon@wfubmc.edu
Abstract:
As outcome measures of cardiac surgery are carefully analyzed, neurologic outcomes are a prominent determinant of overall outcome. Sensitive measures of pre- and postoperative neuropsychologic performance and intraoperative emboli reveal a risk group of patients at an advanced age, with severe generalized atherosclerosis who require cardiac surgery. By using the results of observational studies, we have developed a protocol that uses innovative intraoperative techniques to minimize injury and thus improve outcome.
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