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Updated: Oct 5, 2026

A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
[Myocardial bridge: description, significance, treatment]
C Bourmayan1, M Desnos, C Guérot
1Service de cardiologie I, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris.
Insights
Myocardial bridges, an anomalous coronary artery path, can cause serious heart issues like ischemia and sudden death. Angioplasty and stenting offer effective treatment for symptomatic cases resistant to medication.
Area of Science:
- Cardiology
- Vascular Anatomy
- Clinical Medicine
Context:
- Myocardial bridges are congenital anomalies where a segment of a coronary artery runs through the heart muscle.
- The clinical significance of myocardial bridges ranges from asymptomatic to severe ischemic events.
- Historically, management has been conservative, with surgical intervention reserved for refractory cases.
Purpose:
- To review the current understanding of myocardial bridges and their clinical implications.
- To discuss the diagnostic signs and symptoms associated with symptomatic myocardial bridges.
- To evaluate the evolving treatment strategies for myocardial bridges, including medical, surgical, and interventional approaches.
Summary:
- Myocardial bridges represent an abnormal course of coronary arteries, potentially leading to myocardial ischemia, infarction, or sudden death.
- Symptomatic myocardial bridges manifest with electrocardiographic, scintigraphic, or metabolic evidence of ischemia.
- While medical management is common, angioplasty and stenting have emerged as effective alternatives for patients unresponsive to conservative therapy.
Impact:
- This review highlights the potential severity of myocardial bridges, emphasizing the need for accurate diagnosis and timely intervention.
- It underscores the growing role of percutaneous coronary interventions like angioplasty and stenting in managing complex myocardial bridge cases.
- The findings provide valuable insights for clinicians managing patients with coronary artery anomalies and ischemic heart disease.
Abstract:
The myocardial bridge is a well known anomalous trajectory of the coronary arteries, the significance of which has been discussed for a long time. It now appears that some myocardial bridges may cause myocardial ischaemia with clinical electrocardiographic, scintigraphic or metabolic signs--even myocardial infarction or sudden death. In these symptomatic cases, treatment is usually medical and rarely surgical. In the last few years, angioplasty and stenting have been used more frequently in cases resistant to medical therapy and appear to be an effective alternative to surgery.
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