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Updated: Oct 5, 2026

Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells
Published on: August 1, 2013
[Molecular characterization of aphthous fever virus isolated during the years 1993-1994 in Argentina]
G König1, C Blanco, D Feigelstock
1Instituto de Biotecnología, CICVyA, INTA, CC 77, 1708 Morón, Pcia de Buenos Aires, Argentina.
Abstract:
Nucleotide sequence and phylogenetic analysis of the VP1 structural protein have been used extensively as diagnostic and epidemiological tools for foot and mouth disease virus (FMDV). In this report we have applied this methodology to the analysis of the VP1 coding sequence from FMDV strains isolated in Argentina during 1993-1994. The results demonstrated that the field isolates were related to the vaccine strains used at that time. However the involvement of the vaccine virus appeared to be different for outbreaks caused by FMD viruses type O or C. These data provide a database essential for determining the origin of new epizootics.

